Paraneoplastic Neurological Syndromes Evaluation with Recombx®, Initial Assessment

Test Code

Test Details

Test code: 4711
Type of disorder: Paraneoplastic and Other Antibody Disorders of the CNS
Disease(s) tested for: Paraneoplastic Neurological Syndrome
Tests included:

Technical Information

Clinical Significance: Anti-Hu, anti-Yo, anti-CV2, anti-Ma, anti-Ta, anti-Ri, and anti-Amphiphysin antibodies are found in patients with Stiff-Person syndrome, encephalomyelitis, sensory (motor) neuropathy, cerebellar degeneration, chorea, limbic encephalitis, optic neuritis, autonomic neuropathy, brainstem encephalitis, and/or opsoclonus-myoclonus. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.
Methodology: Automated Nanoliter Scale Immunoassay
Reference Range: See Laboratory Report

CPT Coding

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

CPT: 83520(6)

Specimen Requirements

Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.

Specimen Type: Serum
Specimen Stability: Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 28 days
Specimen Requirements: 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST)
Instructions: Serum must be separated from whole blood within 48 hours of collection.
Alternate Specimen Type: Cerebrospinal Fluid (CSF)
Alternate Specimen Stability: Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 28 days
Alternate Specimen Requirements: 2 mL (0.5 mL minimum) CSF collected in a sterile leak-proof container

Shipping Considerations

Transport Temperature: Refrigerated
Set-up/Analytic Time: 3-5 days

Additional Resources

Letters of Medical Necessity

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