Ganglionic AChR Antibody Test

Test Code

Test Details

Test code: 428
Type of disorder: Paraneoplastic and Other Antibody Disorders of the CNS
Disease(s) tested for: Paraneoplastic Neurological Syndrome
Profiles that contain this test:

Technical Information

Clinical Significance: Detection of anti-ganglionic AChR (α3-AChR ) antibody

Typical Presentation: Rapid onset of severe autonomic failure including orthostatic hypotension, gastrointestinal dysmotility anhidrosis, bladder dysfunction and sicca symptoms.
Methodology: Radioimmunoassay
Reference Range: <55 pMol/L

CPT Coding

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

CPT: 83519(1)

Specimen Requirements

Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.

Specimen Type: Serum
Specimen Stability: Room temperature: 72 hours, Refrigerated: 21 days, Frozen: 4 months
Specimen Requirements: 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST)
Instructions: Serum must be separated from whole blood within 48 hours of collection.

Shipping Considerations

Transport Temperature: Refrigerated
Set-up/Analytic Time: 7-10 days

Additional Resources

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