RyR Autoantibody Test

Test Code
1481

Test Details


Test code: 1481
Type of disorder: Neuromuscular Disorders
Disease(s) tested for: Myasthenia Gravis (MG)
Informed Consent Required: No

Technical Information


Utility: Detects anti-RyR (ryanodine receptor) in the sera of patients with Myasthenia Gravis (MG). Other striational antibodies, such as titin, are rarely found in acetylcholine receptor (AChR) antibody-negative MG. Anti-titin is detected in 20% to 40% of all MG patients and anti-RyR in 13% to 38%. Anti-titin (49% to 95%) and anti-RyR (70% to 80%) are frequently found in thymoma associated-MG cases.
Methodology: Western Blot
Reference Value: <1:8000

CPT Coding


The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

CPT: 84181

Specimen Requirements


Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.

Specimen Type: Serum
Specimen Stability: Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 28 days
Adult Preferred Volume: 2 mL
Adult Minimum Volume: 0.5 mL
Collection Tube: Red-top tube or Serum Separator Tube (SST)

Shipping Considerations


Storage Conditions: See Specimen Stability
Shipping Conditions: Refrigerated
Test Turnaround: 7-14 days

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