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Test Catalog
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ADmark® Alzheimer's Evaluation |
#178 |
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| Type of Disorder: |
Dementia |
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| Typical Presentation: |
Dementia |
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| Indications for Testing: |
Dementia |
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| Disease(s) tested for: |
Alzheimer's disease |
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| Test Details |
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| Test Code: |
178 |
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| Profile includes: |
ADmark® ApoE Genotype Analysis & Interpretation (Symptomatic), ADmark® Phospho-Tau/Total-Tau/Ab42 CSF Analysis & Interpretation (Symptomatic)
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Technical Information |
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| Utility: |
Detection of ApoE2, E3, E4 alleles and levels of Phosphorylated-Tau protein, Total-Tau protein, and A?42 |
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| Methodology: |
Restriction Fragment Length Polymorphism (RFLP) |
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| Reference Value: |
Correlation of levels of markers of Phosphorylated-Tau, Total-Tau, and Ab42, Presence of ApoE2, E3, E4 alleles |
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| CPT Code(s): |
83520(3), 83891(1), 83892(4), 83896(10), 83908(4), 83912(1) |
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| Patents: |
4,666,829, 5,593,846, 5,508,167, 5,861,257, 6,027,896, 5,843,779, 6,114,133, & 6,121,003 |
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| Shipping Considerations |
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| Preferred Specimen Requirements |
| Type: |
Cerebrospinal Fluid (CSF) and whole blood |
| Minimum Volume: |
2ml CSF and 10ml Blood |
| Collection Tube: |
Polypropylene Transfer Tube (glass and polystyrene not acceptable) and Lavender Top (EDTA) |
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| Storage Conditions: |
CSF - Refrigerate if necessary for a maximum of 24 hours, Blood-room temperature, avoid freezing |
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| Shipping Conditions: |
CSF - Refrigerated or frozen on dry ice, Buccal Swabs-in a collection packet |
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| Test Turnaround: |
7-14 days |
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