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Neuromyelitis Optica (NMO) #193
Type of Disorder: Multiple Sclerosis
Typical Presentation: Symptoms of NMO include optic neuritis, and transverse myelitis, weakness, sometimes paralysis of the arms and legs, in addition to sensory disturbances and loss of bowel and bladder control.
Indications for Testing: Rule out NMO in patients with optic neuritis and transverse myelitis and distinguishing this disease from multiple sclerosis.
Disease(s) tested for: Neuromyelitis Optica
Test Details
Test Code: 193
Informed Consent Required: No
Special Notes: NMO-IgG antibodies are also present in patients with longitudinally extensive transverse myelitis (LETM) without optic neuritis, which is thought to be a precurser to NMO.
Technical Information
Utility: Confirm suspected cases of NMO and assist in making a differential diagnosis and identifying the cause of MS-like symptoms in the patient. An accurate diagnosis will further help predict disease course and provide direction in treatment options.
Methodology: ELISA
Reference Value: Positive: Presence of NMO autoantibodies
CPT Coding
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
CPT 2013: 83516(1)
Shipping Considerations
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
Preferred Specimen Requirements
Type: Serum
Minimum Volume: 2 mL
Collection Tube: Red top
Storage Conditions: Refrigerate, avoid freezing
Shipping Conditions: Room temperature, avoid freezing. Ship within 24 hours, Monday-Friday
Test Turnaround: 5-7 days
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