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NeoEncephalitis Paraneoplastic Profile with Recombx #439
Type of Disorder: Paraneoplastic Disorders
Typical Presentation: Limbic encephalitis including confusion/dementia, depression/anxiety and/or seizures or hallucinations, usually with MRI changes in medial temporal lobes
Disease(s) tested for: Paraneoplastic neurological disorders (PNDs), CV2, Hu, Ma, Ta, VGKC, Amphiphysin, GAD, NMDA Receptor (NR1), Stiff Person Syndrome
Test Details
Test Code: 439
Profile includes: Amphiphysin Antibody Test, GAD Antibody Test, NMDA Receptor (NR1) Antibody Test, Recombx™ MaTa Autoantibody Test, Recombx™ CV2 Antibody Test, Recombx™ Hu Autoantibody Test, VGKC Antibody Test
Informed Consent Required: No
Medicare ABN Required: No
Technical Information
Utility: Detection of anti-Hu, anti-CV2, anti-Ma, and anti-Ta antibodies using recombinant human antigens; antibodies to voltage gated potassium channels (VGKC) using RIA and Amphiphysin using Western Blot, GAD using ELISA and NMDA receptor (NR1) using IFA
Methodology: Western blot, immunoprecipitation, ELISA, IFA
Reference Value: Please see individual test listings.
Patents: 7,329,499, 6,193,948, 5,807,705, 6,387,639, 7,026,450
CPT Coding
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Stacked CPT Code(s): 83516(1), 83519(1), 83520(1), 84181(1), 84182(2), 86255(1)
Shipping Considerations
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
Preferred Specimen Requirements
Type: Serum
Minimum Volume: 3 mL
Collection Tube: Red top
Storage Conditions: Refrigerate if not shipped same day. Serum stable up to three days. Ship whole blood immediately.
Shipping Conditions: Room temperature, avoid freezing. Ship same day.
Test Turnaround: 28 days
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