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Test Catalog
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Neonatal Diabetes Mellitus Evaluation |
#882 |
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| Type of Disorder: |
Diabetes |
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| Typical Presentation: |
Insulin-sensitive hyperglycemia in newborns |
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| Indications for Testing: |
Insulin-sensitive hyperglycemia in newborns or infants, Family history of neonatal diabetes mellitus |
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| Disease(s) tested for: |
Neonatal Diabetes Mellitus |
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| Test Details |
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| Test Code: |
882 |
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| Profile includes: |
ABCC8 (NDM) DNA Sequencing Test, GCK (NDM) DNA Sequencing Test, INS (NDM) DNA Sequencing Test, IPF1 (NDM) DNA Sequencing Test, KCNJ11 (NDM) DNA Sequencing Test
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Technical Information |
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| Utility: |
Detects mutations (including point mutations, deletions, insertions, and rearrangements) in the coding sequences of the genes KCNJ11, ABCC8, INS, GCK, and IPF1 |
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| Methodology: |
Polymerase Chain Reaction (PCR), DNA sequencing of entire protein coding regions of genes |
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| Reference Value: |
No sequence variation detected |
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| Patents: |
5,541,060, 6,274,310, 6,054,313 |
| CPT Coding |
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The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding
is the sole responsibility of the billing party.
Please direct any questions regarding coding to
the payer being billed.
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| Stacked CPT Code(s): |
83891(1), 83898(57), 83904(57), 83909(57), 83912(1)
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| Shipping Considerations |
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| Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form. |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
10 mL (Pediatric minimum: 2 mL) |
| Collection Tube: |
Lavebnder top (EDTA) |
| Stability: |
Hemolysis may compromise DNA recovery and integrity after 48 hrs |
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| Storage Conditions: |
Room temperature, avoid freezing |
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| Shipping Conditions: |
Overnight at room temperature (specimen arrival must be less than 24 hrs after collection); ship Monday through Thursday only |
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| Test Turnaround: |
2-8 weeks |
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