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Test Catalog
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Complete Alport Syndrome Evaluation |
#759 |
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| Type of Disorder: |
Kidney Disorders, Alport Syndrome |
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| Typical Presentation: |
Hematuria, proteinuria and progressive renal failure, often leading to bilateral sensorineural hearing loss and ocular defects |
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| Disease(s) tested for: |
Alport Syndrome |
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| Test Details |
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| Test Code: |
759 |
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| Profile includes: |
COL4A3 DNA Sequencing Test, COL4A4 DNA Sequencing Test, COL4A5 Sequencing and Deletion Analysis
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Technical Information |
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| Utility: |
Detects mutations in the COL4A3, 4, 5 genes and deletions in COL4A5 |
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| Methodology: |
DNA sequencing, Multiplex Ligation-dependent Probe Amplification |
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| Reference Value: |
No sequence variation or deletion detected |
| CPT Coding |
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The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding
is the sole responsibility of the billing party.
Please direct any questions regarding coding to
the payer being billed.
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| Stacked CPT Code(s): |
83891(1), 83898(151), 83900(1), 83901(69), 83904(99), 83909(153), 83912(1), 83914(71)
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| Shipping Considerations |
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| Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form. |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
15 mL |
| Collection Tube: |
Lavender top (EDTA) |
| Stability: |
Hemolysis may compromise DNA recovery and integrity after 48 hrs |
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| Storage Conditions: |
Room temperature, avoid freezing |
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| Shipping Conditions: |
Overnight at room temperature (specimen arrival must be less than 24 hrs after collection); ship Monday through Thursday only |
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| Test Turnaround: |
2-8 weeks |
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