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Test Catalog
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TCF1 (MODY3) DNA Sequencing and Deletion Test |
#804 |
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| Type of Disorder: |
Diabetes, Maturity-Onset Diabetes of the Young (MODY) |
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| Typical Presentation: |
Non-ketotic hyperglycemia in non-obese individuals of any age |
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| Indications for Testing: |
Non-ketotic insulin-sensitive hyperglycemia in individuals of any age;
Family history of mutations in TCF1 |
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| Disease(s) tested for: |
MODY3, Maturity-Onset Diabetes of Young (MODY) |
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| Test Details |
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| Test Code: |
804 |
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| Profiles that contain this test: |
Diabetes Antibody Panel with Negative Reflex to MODY 1, 2, 3, Monogenic Diabetes (MODY) Evaluation
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Technical Information |
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| Utility: |
Detects deletions and mutations in the HNF1A gene |
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| Methodology: |
DNA sequencing, Multiplex Ligation-dependent Probe Amplification |
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| Reference Value: |
No sequence variation or deletion detected |
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| Patents: |
6,187,533 |
| CPT Coding |
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The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding
is the sole responsibility of the billing party.
Please direct any questions regarding coding to
the payer being billed.
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| Stacked CPT Code(s): |
83891(1), 83898(10), 83900(1), 83901(42), 83904(10), 83909(11), 83912(1), 83914(44) |
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| Shipping Considerations |
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| Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form. |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
10 mL (pediatric minimum: 2 mL) |
| Collection Tube: |
Yellow or lavender top |
| Stability: |
Hemolysis may compromise DNA recovery after 48 hrs |
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| Storage Conditions: |
For short periods (until shipped) at 4oC |
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| Shipping Conditions: |
Overnight at room temperature (specimen arrival must be less than 24 hrs after collection); Ship Monday through Thursday only |
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| Test Turnaround: |
2 - 8 weeks |
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