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Test Catalog
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Pheochromocytoma Evaluation |
#889 |
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| Type of Disorder: |
Family Cancer Syndromes |
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| Typical Presentation: |
Headache, palpitations, diaphoresis, hypertension |
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| Indications for Testing: |
Clinical diagnosis of or suspician of Pheochromocytoma (PHEO), family history of PHEO |
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| Disease(s) tested for: |
Pheochromocytoma |
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| Test Details |
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| Test Code: |
889 |
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| Profile includes: |
MEN2 (RET) Evaluation, SDHB DNA Sequencing Test, Von Hippel-Lindau Syndrome (VHL) Evaluation
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Technical Information |
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| Utility: |
Detects mutations in the coding sequences of the VHL, RET and SDHB genes |
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| Methodology: |
Polymerase Chain reaction (PCR); DNA Sequencing of the entire coding region of the gene. |
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| Reference Value: |
No mutation detected |
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| CPT Code(s): |
83891(1); 83898(31); 83904(31); 83909(1); 83912(1) |
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| Shipping Considerations |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
10 mL (Pediatric minimum: 2 mL) |
| Collection Tube: |
Lavender top (EDTA) |
| Stability: |
Hemolysis may compromise DNA recovery and integrigy after 48 hours |
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| Storage Conditions: |
For short periods (until shipped) at 4 degrees C |
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| Shipping Conditions: |
Overnight at room temperature (specimen arrival must be less than 24 hours after collection) Ship Monday through Thursday only |
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| Test Turnaround: |
2 - 8 weeks |
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