|
Test Catalog
|
|
LRP5 Idiopathic Osteoporosis (IOP) DNA Sequencing Test |
#821 |
|
| Type of Disorder: |
Bone Fragility |
|
| Typical Presentation: |
Unusual fractures due to minor trauma |
|
| Indications for Testing: |
Unusual bone fragility in otherwise healthy individuals; Family history of idiopathic osteoporosis or OPPG |
|
| Disease(s) tested for: |
Idiopathic Osteoporosis |
|
| Test Details |
|
| Test Code: |
821 |
|
| Informed Consent Required: |
Yes |
|
| Medicare ABN Required: |
Yes |
|
| Technical Information |
|
| Utility: |
Detects mutations (including point mutations, deletions, insertions, and rearrangements) in the coding sequences of the gene LRP5 |
|
| Methodology: |
Poltymerase Chain Reaction (PCR), DNA sequencing of entire coding region of gene |
|
| Reference Value: |
No mutation detected |
|
| CPT Code(s): |
83891(1), 83898(24), 83904(24), 83909(1), 83912(1) |
|
| Patents: |
6,555,654, 6,545,137 |
|
| Shipping Considerations |
|
| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
10 mL (Pediatric minimum: 2 mL) |
| Collection Tube: |
Lavender top (EDTA) |
|
| Storage Conditions: |
For short periods (until shipped) at 4°C |
|
| Shipping Conditions: |
Overnight at room temperature (specimen arrival must be less than 24 hours after collection) Ship Monday through Thursday only |
|
| Test Turnaround: |
2 - 8 weeks |
|
|
|
