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ADmark® PS-2 DNA Sequencing Test	#169

Test Details

Type of Disorder:	Dementia

Typical Presentation:	Progressive demential with onset before age 65 with a positive family history of early-onset Alzheimer's disease

Disease(s) tested for:	Alzheimer's disease


Test Code:	169

Profiles that contain this test:	ADmark® Early Onset Alzheimer's Evaluation

Informed Consent Required:	Yes

Medicare ABN Required:	Yes

Special Notes:	Athena does not perform this test for individuals under the age of 18.

Technical Information

Utility:	Detects sequence variations in the presenilin 2 (PS-2) gene

Methodology:	Polymerase Chain Reaction (PCR) and DNA sequencing

Reference Value:	No sequence variation detected

CPT Code(s):	83891(1), 83898(10), 83904(10), 83909(1), 83912(1)

Patents:	5,840,540

Shipping Considerations

Preferred Specimen Requirements
Type:	Whole blood
Minimum Volume:	10 ml
Collection Tube:	Lavender top (EDTA)

Storage Conditions:	Refrigerate if necessary for a maximum of 24 hours

Shipping Conditions:	Room temperature. Ship within 24 hours, Monday-Thursday only.

Test Turnaround:	14-21 Days

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