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Test Catalog
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Complete CADASIL Evaluation |
#421 |
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| Type of Disorder: |
Stroke/Thrombosis |
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| Typical Presentation: |
Hereditary cause of stroke, dementia, migraine with aura, mood disorders |
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| Disease(s) tested for: |
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) |
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| Test Details |
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| Test Code: |
421 |
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Special Notes: |
Athena sequences all 23 exons where all known mutations for CADASIL have been found. |
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| Technical Information |
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| Utility: |
Detects mutations in the Notch3 gene |
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| Methodology: |
Polymerase Chain Reaction (PCR) and DNA sequencing |
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| Reference Value: |
No mutation detected |
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| CPT Code(s): |
83891(1), 83898(23), 83904(23), 83909(1), 83912(1) |
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| Patents: |
6,537,775, 6,995,257, 7,138,234 |
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| Shipping Considerations |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
10ml |
| Collection Tube: |
Lavender top (EDTA) |
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| Storage Conditions: |
Refrigerate, avoid freezing |
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| Shipping Conditions: |
Room temperature. Ship within 24 hours, Monday -Thursday only. |
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| Test Turnaround: |
21-28 days |
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