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Test Catalog
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OtoDx™ Aminoglycoside Hypersensitivity Test |
#327 |
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| Type of Disorder: |
Hearing Loss |
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| Typical Presentation: |
Sensorineural, nonsyndromic hearing loss often associated with aminoglycoside antibiotic exposure |
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| Disease(s) tested for: |
Hearing loss |
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| Test Details |
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| Test Code: |
327 |
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| Informed Consent Required: |
Yes |
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| Medicare ABN Required: |
Yes |
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| Special Notes: |
The A1555G mutation in the mitochondrial genome is known to cause hearing loss in patients exposed to aminoglycoside antibiotics. This mutation is also associated with sensorineural hearing loss without aminoglycoside exposure. |
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| Technical Information |
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| Utility: |
Detects the A1555G mutation in the mitochondrial genome |
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| Methodology: |
Restriction Fragment Length Polymorphism (RFLP) |
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| Reference Value: |
No mutation detected |
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| CPT Code(s): |
83891(1), 83892(1), 83894(1), 83898(1), 83912(1) |
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| Patents: |
5,506,101 |
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| Shipping Considerations |
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| Preferred Specimen Requirements |
| Type: |
Whole blood |
| Minimum Volume: |
20ml |
| Collection Tube: |
Lavender top (EDTA) |
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| Storage Conditions: |
Refrigerate |
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| Shipping Conditions: |
Room temperature, avoid freezing. Ship within 24 hours of draw, Monday -Thursday only. |
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| Test Turnaround: |
7-14 days |
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