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What is Myasthenia Gravis

Overview | Treatment Options | Benefits of Testing | VGR Presentation

What is Myasthenia Gravis

Myasthenia Gravis (MG) is a common autoimmune neuromuscular disorder affecting 1 in 5,000 people.  It is characterized by muscle weakness that increases with exercise and improves with inactivity.1

In MG, the normal transmission of nerve impulses to muscle fibers is blocked at the neuromuscular junction.  The acetylcholine (AChR) neurotransmitter is unable to bind to receptors in the post-synaptic region, preventing muscle contraction.2

Potential Treatment Options

Athena’s Diagnostic Testing Services for MG

Test Name Test Code Clinical Utility
 
AChR/MuSK Reflexive Antibody Test (Now with MuSK Quantitative Titers Antibody Test) 483 Detects antibodies to AChR receptor in patients with MG, negative results reflex to MuSK Quantitative Titers Antibody Test
 
MuSK Quantitative Titers Antibody Test 482 Detects MuSK antibody titers in patients with MG that are seronegative for AChR antibodies
 

1. http://www.myasthenia.org/
2. www.ninds.nih.gov/disorders/myasthenia_gravis

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